FROM R&D TO PRODUCTION
Continuous and disturbance-free measuring of key metabolic parameters is critical for cell biologists. Cell growth and metabolic activity can be measured instantaneously and such derived data can be used to trigger bioprocess control actions.
It is not only the sophisticated labs of biopharmaceutical companies who benefit from the features offered by CITSens Bio but also the many investigators in the different fields of basic cell biology research. Frequent manual interventions for sample taking or optical examination harm cell cultures and disturb their growth. Negative aspects of disturbing growing cell cultures are:
lower cell density resulting in lower product yield
metabolic stress and gene expression due to environmental change (carbon dioxide, temperature, pH Shift, seize of agitation)
no information on their actual metabolic state by optical inspection
Using CITSens Bio (combining the power of electrochemistry and radio transmission) cell biologists in R&D and production continuously control the growth and metabolism of active cells in real time. With CITSens Bio the optimal time point for interventions such as harvest or optical control are ensured. Cases of contamination are registered at the earliest time possible.